ON-GOING STUDENT PROJECTS
If you're interested in joining the group – drop me an email: t.a.hamlin@vu.nl
If you're interested in joining the group – drop me an email: t.a.hamlin@vu.nl
Lewis Acid Catalysis
How Lewis Acids Catalyze Diels-Alder Reactions
P. Vermeeren, T. A. Hamlin, I. Fernandez,* F. M. Bickelhaupt* Angew. Chem. 2020, 132, accepted; Angew. Chem. Int. Ed. 2020, 59, accepted How Dihalogens Catalyze Michael Addition Reactions T. A. Hamlin, I. Fernandez,* F. M. Bickelhaupt* Angew. Chem. 2019, 131, 9015–9020; Angew. Chem. Int. Ed. 2019, 58, 8922–8926 Highlighted in ChemistryWorld |
SN2 Reactions
Ambident Nucleophilic Substitution: Understanding Non-HSAB Behaviour through Activation Strain and Conceptual DFT Analyses
T. Bettens, M. Alonso, F. De Proft,* T. A. Hamlin,* F. M. Bickelhaupt* Chem. Eur. J. 2020, 26, in press Nucleophilic Substitution in Solution: Activation Strain Analysis of Weak and Strong Solvent Effects T. A. Hamlin, B. van Beek, L. P. Wolters, F. M. Bickelhaupt* Chem. Eur. J. 2018, 24, 5927–5938 |
Cycloaddition Reactions
Structural Distortion of Cycloalkynes Influences Cycloaddition Rates by both Strain and Interaction Energies
T. A. Hamlin,† B. J. Levandowski,† A. K. Narsaria, K. N. Houk,* F. M. Bickelhaupt* Chem. Eur. J. 2019, 25, 6342–6348 [Cover] The Role of Orbital Interactions and Activation Strain (Distortion Energies) on Reactivities in the Normal and Inverse Electron-Demand Cycloadditions of Strained and Unstrained Cycloalkenes B. J. Levandowski,† T. A. Hamlin,† F. M. Bickelhaupt,*K. N. Houk* J. Org. Chem. 2017, 82, 8668–8675 (Most Read Article July, August, September 2017) |